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White powder Peptide GDF-8 Dosage growth differentiation factor 8 1mg Myostatin
White powder Peptide GDF-8 Dosage growth differentiation factor 8 1mg Myostatin
Supply Ability:
100000 Box/Boxes per 0
Port:
Shenzhen
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Quantity:
Box
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Place of Origin:
China (Mainland)
Brand Name:
HZ
Model Number:
GDF-8
Packaging & Delivery
as required
Product Description


White powder Peptide GDF-8 Dosage growth differentiation factor 8 1mg Myostatin



Quick Details:


Product name:Myostatin GDF-8

Purity:95%

Specification:1mg/vial

Appearance:White powder

Certificate:GMP

Storage:Dry Cool Place

Grade:Medicine Grae



What is the GDF 8 / Myostatin ?


Myostatin (also known as growth differentiation factor 8, abbreviated GDF-8) is a myokine, a protein produced and released by myocytes that acts on muscle cells' autocrine function to inhibit myogenesis: muscle cell growth and differentiation. In humans it is encoded by the MSTN gene. Myostatin is a secreted growth differentiation factor that is a member of the TGF beta protein family.

Structure and mechanism of action

Human myostatin consists of two identical subunits, each consisting of 109 (NCBI database claims human myostatin is 375 residues long) amino acid residues. Its total molecular weight is 25.0 kDa. The protein is inactive until a protease cleaves the NH2-terminal, or "pro-domain" portion of the molecule, resulting in the active COOH-terminal dimer.


Myostatin also inhibits Akt, a kinase that is sufficient to cause muscle hypertrophy, in part through the activation of protein synthesis. However, Akt is not responsible for all of the observed muscle hyperthrophic effects which are mediated by myostatin inhibition Thus myostatin acts in two ways: by inhibiting muscle differentiation, and by inhibiting Akt-induced protein synthesis.



Myostatin Usage


A growth factor that regulates the size of muscles beginning in early embryonic development and continuing throughout life. Myostatin acts by inhibiting the growth of muscles, It prevents them from growing too large. Myostatin is also known as growth and differentiation factor 8 (GDF-8)



How does GDF-8 work?


Some studies show that the lack of myostatin gives rise to impressive results in the increase of muscle mass both in humans and in animals. In bones specifically, the lack of myostatin increases its mineral density, resulting in an increase of the calcium levels of the organism. GDF-8 is stored in bones and it is necessary for the correct functionality of the heart, muscles, and nerves as well as for blood clotting.



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